REGULATION OF ACTIN DYNAMICS IN THE C. ELEGANS SOMATIC GONAD

Regulation of Actin Dynamics in the C. elegans Somatic Gonad

Regulation of Actin Dynamics in the C. elegans Somatic Gonad

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Bed linen The reproductive system of the hermaphroditic nematode C.elegans consists of a series of contractile cell types—including the gonadal sheath cells, the spermathecal cells and the spermatheca–uterine valve—that contract in a coordinated manner to regulate oocyte entry and exit of the fertilized embryo into the uterus.Contraction is driven by acto-myosin contraction and relies on the development and maintenance of specialized EYE PRO acto-myosin networks in each cell type.

Study of this system has revealed insights into the regulation of acto-myosin network assembly and contractility in vivo.

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